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Gulf Press > Technology > Here are the 49 US AI startups that have raised $100M or more in 2025
Technology

Here are the 49 US AI startups that have raised $100M or more in 2025

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Last updated: 2025/11/30 at 9:39 PM
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The artificial intelligence (AI) sector continues to experience explosive growth, with 2024 shaping up to be a landmark year for investment. As we move into the final weeks of 2024, the pace of funding hasn’t slowed, and in fact, has matched the previous year’s momentum. This surge in AI funding demonstrates the ongoing confidence in the technology’s potential to transform industries.

Contents
November Funding HighlightsOctober’s Momentum ContinuesSeptember: Infrastructure and Research Take Center StageAugust & Beyond: Diverse Applications Attract Capital

According to data compiled by TechCrunch, 49 startups secured funding rounds of $100 million or more in 2024. Notably, three companies achieved multiple “mega-rounds,” and seven raised over $1 billion in a single funding cycle. The trend is continuing into 2025, with an equivalent number of companies already reaching the $100 million mark, and a significant increase in those securing follow-on investments. This indicates a maturing ecosystem and a willingness of investors to double down on promising AI ventures.

The Rise of AI Investment: A Look at 2024’s Biggest Deals

The substantial influx of capital is fueling innovation across a wide range of AI applications, from generative media and healthcare to enterprise software and legal technology. Several key themes are emerging, including a focus on AI infrastructure, the development of specialized AI models for specific industries, and the increasing integration of AI into existing workflows. This investment is not limited to early-stage startups; established companies are also participating, seeking to leverage AI to enhance their offerings and maintain a competitive edge.

November Funding Highlights

November saw continued strong investment in the AI space. Anysphere, the company behind the popular coding platform Cursor, led the way with a massive $2.3 billion raise, valuing the company at $29.3 billion. This round highlights the growing demand for AI-powered tools that assist developers. Parallel, focused on building web infrastructure for AI agents, secured a $100 million Series A, co-led by Index Ventures and Kleiner Perkins. Hippocratic AI, a healthcare AI agent startup, also raised significant capital, closing a $126 million Series C at a $3.5 billion valuation.

October’s Momentum Continues

October brought a flurry of activity, with Fireworks AI raising $250 million in a Series C round, achieving a $4 billion valuation. The company’s platform enables users to build AI applications using open-source models, catering to the growing demand for customizable AI solutions. Uniphore, an enterprise AI startup, reached a $2.5 billion valuation after a $260 million Series F round, attracting investment from tech giants like Snowflake and Nvidia. Sesame, a voice AI company, secured $250 million in a Series B round, co-led by Sequoia and Spark Capital. Further investment came with OpenEvidence ($200M Series C), Lila Sciences ($350M Series A), Reflection AI ($2B Series B), and EvenUp ($150M Series E).

September: Infrastructure and Research Take Center Stage

September’s funding rounds underscored the importance of both AI infrastructure and fundamental research. Cerebras Systems, an AI infrastructure company, raised a substantial $1.1 billion Series G, valuing it at $8.1 billion. Modular, also focused on AI infrastructure, secured $250 million. Several companies focused on AI research itself also attracted significant investment, including Periodic Labs ($300M seed), Upscale AI ($100M seed), Groq ($750M Series E), and Invisible Technologies ($100M).

August & Beyond: Diverse Applications Attract Capital

The trend of diverse applications garnering attention continued in August and the subsequent months, with funding spread across different sectors. EliseAI ($250M Series E) is building AI for healthcare and housing, Decart ($100M) concentrating on AI research. July saw substantial funding for generative media platform Fal ($125M Series C) and AI coding startup Turing ($111M Series E). Throughout the remainder of 2024 and into the beginning of 2025, investments continued including significant a sizable round for OpenAI ($40B).

The Future of AI Funding

The current investment climate suggests that AI companies will remain a prime target for venture capital in the near future. However, the focus may shift toward profitability and sustainable business models as the market matures. Investors will likely scrutinize companies’ ability to generate revenue and demonstrate a clear path to long-term success. The continued development of machine learning and the broadening scope of deep learning applications will also play a crucial role in attracting future investment.

Looking ahead, the performance of these funded companies and the emergence of new, innovative startups will be key indicators of the sector’s continued growth. Potential regulatory changes and the ethical considerations surrounding AI development will also significantly shape the landscape. Monitoring the progress of these ventures and the evolving industry dynamics will be critical for understanding the future of AI investment.

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News Room November 30, 2025
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