By using this site, you agree to the Privacy Policy and Terms of Use.
Accept
Gulf PressGulf Press
  • Home
  • Gulf News
    • Saudi Arabia
    • UAE24/7
    • Kuwait
    • Qatar
    • Bahrain
    • Oman
  • World
  • Business
    • Market DataLive
    • Finance
    • Economy
    • Energy
    • Crypto
    • ForexHot
    • Tech
  • Sports
  • Lifestyle
  • Videos
Search
Countries
  • Saudi Arabia
  • UAE
  • Kuwait
  • Qatar
  • Bahrain
  • Oman
More Topics
  • Technology
  • Health
  • Entertainment
  • Crypto
  • Forex
  • Stocks
Site Links
  • Business Hub
  • Trending
  • Weather
  • Customize Interests
  • Bookmarks
  • Newsletter
  • Terms
  • Press Release
  • Advertise
  • Contact
© 2023 Gulf Press. All Rights Reserved.
Reading: Which is more important: a maternal or paternal history of disease?
Share
Notification Show More
Recent Saved
Workers in Bucharest face challenges as temperatures rise
World
Dress code guidelines for the Qatari government sector during office hours
Qatar
Court rules in favor of worker after company dismisses him for salary deductions over 6 years, awarding BD 27,000.
Bahrain
UAE to See Almost 30,000 New Millionaires in 5 Years
UAE
Proposed New Labor Law in Bahrain Targets Increasing Job Opportunities
Bahrain
Latest News
Ferrero’s Social Responsibility Project Kinder Joy of moving Beats Traditional PE Curriculum, Tapping into the Cognitive Functions, Motor Coordination and Life Skills of Students
Lifestyle
UAE Ranks Among Top Rugby Markets on TOD as British & Irish Lions Tour Kicks Off
Sports
Darven: A New Leap in AI-Powered Legal Technology Launching from the UAE to the World
Tech
Beat the Heat This Summer with a Chill Out on Dubai Marina
World
Historic Italian City of Assisi to Host International Exhibition “Jordan: Dawn of Christianity”
World
Jordan to Host Iraq in the Final Round of the Asian World Cup Qualifiers After Securing Historic Spot
Sports
The Myriad Redefines Student Living for a Mobile, Urban Generation
UAE
L’Oréal Paris Welcomes Yasmine Sabri as New Brand Ambassador for the Middle East
Lifestyle
Roland Garros 2025: A New Era of Viewing, A Tribute to Legends, and Moments to Remember
Sports World
Bitget Celebrates Bitcoin Pizza Day by Distributing Over 5000 Pizzas in Over 20 Cities Worldwide
Crypto
Aa
Gulf PressGulf Press
Aa
  • Gulf News
  • World
  • Business
  • Entertainment
  • Lifestyle
  • Sports
  • Videos
Search
  • Home
    • Videos
    • Business Hub
    • Trending
  • Gulf
    • Saudi Arabia
    • UAE
    • Kuwait
    • Qatar
    • Bahrain
    • Oman
  • Business
    • Market Data
    • Crypto
    • Economy
    • Energy
    • Finance
    • Forex
    • Tech
  • More News
    • World
    • Lifestyle
    • Entertainment
    • Sports
Have an existing account? Sign In
Follow US
  • Terms
  • Press Release
  • Advertise
  • Contact
© 2023 Gulf Press. All Rights Reserved.
Gulf Press > Health > Which is more important: a maternal or paternal history of disease?
Health

Which is more important: a maternal or paternal history of disease?

News Room
Last updated: 2024/07/06 at 3:26 PM
News Room
Share
4 Min Read
SHARE

Genetics play a crucial role in the development of Alzheimer’s disease, with inherited genes from both parents increasing a person’s risk. The APOE4 gene is a top genetic risk factor, along with 17 other genetic variants associated with the condition. Recent research from Mass General Brigham suggests that a person’s inherited Alzheimer’s genetic risk may depend on whether they receive it from their biological mother or father. A study published in JAMA Neurology found that participants with a maternal history of memory issues and a paternal history of early-onset memory impairment were linked to higher beta-amyloid levels in the brain, a key biomarker for Alzheimer’s. The study involved 4,400 participants from the A4 study aimed at Alzheimer’s disease prevention.

Despite not knowing the exact cause of Alzheimer’s disease, researchers have identified various factors involved, including genetics. The study by Mass General Brigham found that maternal and paternal history of dementia or memory loss may have different impacts on a person’s risk for Alzheimer’s disease. Maternal history of any age at onset and paternal history of early-onset dementia were associated with increased risk, while paternal history of late-onset dementia was not. This suggests a preferential maternal inheritance of Alzheimer’s disease and has important implications for risk stratification and early identification of the condition.

The research also raises questions about mitochondrial inheritance and genomic imprinting as potential mechanisms influencing Alzheimer’s risk. Dysfunction of the mitochondria, the cellular powerhouses, has been associated with dementia symptoms in the past. The study found that genetic information from the mother might have a stronger impact on the risk of Alzheimer’s disease, possibly due to these underlying genetic mechanisms. The study results may be influenced by disparities in life expectancies between males and females, with fewer fathers living long enough to develop dementia among the study participants aged 65 and older.

Experts in the field of Alzheimer’s disease emphasize the importance of understanding the heritability of the condition for early detection, personalized treatment, and prevention strategies. The study’s findings highlight the need for nuanced approaches in assessing Alzheimer’s risk and targeting high-risk individuals for intervention. Genetic and familial aspects of Alzheimer’s disease remain essential areas of investigation for improving patient outcomes and reducing the societal burden of the disease. Further research into how genetics and family history impact a person’s risk of developing Alzheimer’s disease is crucial for advancing personalized care plans and discovering new therapeutic interventions.

Overall, the study by Mass General Brigham sheds light on the complex interplay between genetics, family history, and Alzheimer’s disease risk. Understanding the impact of maternal and paternal inheritance patterns on Alzheimer’s risk can lead to more personalized and effective interventions for individuals at higher risk of developing the condition. Continued research into the genetic and familial aspects of Alzheimer’s disease is essential for advancing early detection, personalized treatment, and prevention strategies, ultimately improving patient outcomes and reducing the societal burden of the disease.

Sign Up For Daily Newsletter

Be keep up! Get the latest breaking news delivered straight to your inbox.
I have read and agree to the terms & conditions
By signing up, you agree to our Terms of Use and acknowledge the data practices in our Privacy Policy. You may unsubscribe at any time.
News Room July 6, 2024
Share this Article
Facebook Twitter Copy Link Print
Previous Article Watch: Sachin Tendulkar receives applause and cheers at Wimbledon before Norrie vs Zverev match – News
Next Article Government launches two major housing projects as part of Land Development Programme
Leave a comment Leave a comment

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Stay Connected

235.3k Followers Like
69.1k Followers Follow
56.4k Followers Follow
136k Subscribers Subscribe
- Advertisement -
Ad imageAd image

Latest News

Ferrero’s Social Responsibility Project Kinder Joy of moving Beats Traditional PE Curriculum, Tapping into the Cognitive Functions, Motor Coordination and Life Skills of Students
Lifestyle July 14, 2025
UAE Ranks Among Top Rugby Markets on TOD as British & Irish Lions Tour Kicks Off
Sports July 6, 2025
Darven: A New Leap in AI-Powered Legal Technology Launching from the UAE to the World
Tech July 1, 2025
Beat the Heat This Summer with a Chill Out on Dubai Marina
World July 1, 2025

You Might also Like

Health

Mindfulness could be equally effective as antidepressants

October 17, 2024
Health

What is the impact of caffeine on the risk of developing diseases?

October 17, 2024
Health

Scientists discover combination of 14 genes that enhance outcomes

October 16, 2024
Health

Seizure medication demonstrates potential in individuals with no genetic risk

October 16, 2024
Health

Heart disease increases risk, heparin can postpone onset

October 16, 2024
Health

What type of breakfast is most effective for weight loss in women compared to men?

October 15, 2024
Health

How does the brain remove “waste” to protect itself?

October 14, 2024
Health

How does stress, sleep, and gut imbalances affect it?

October 13, 2024
//

Gulf Press is your one-stop website for the latest news and updates about Arabian Gulf and the world, follow us now to get the news that matters to you.

Quick Link

  • Privacy Policy
  • Terms of ue
  • Advertise
  • Contact

How Topics

  • Gulf News
  • International
  • Business
  • Lifestyle

Sign Up for Our Newsletter

Subscribe to our newsletter to get our latest news instantly!

I have read and agree to the terms & conditions
Gulf PressGulf Press
Follow US

© 2023 Gulf Press. All Rights Reserved.

Join Us!

Subscribe to our newsletter and never miss our latest news, podcasts etc..

I have read and agree to the terms & conditions
Zero spam, Unsubscribe at any time.

Removed from reading list

Undo
Welcome Back!

Sign in to your account

Lost your password?