By using this site, you agree to the Privacy Policy and Terms of Use.
Accept
Gulf PressGulf Press
  • Home
  • Gulf News
    • Saudi Arabia
    • UAE24/7
    • Kuwait
    • Qatar
    • Bahrain
    • Oman
  • World
  • Business
    • Market DataLive
    • Finance
    • Economy
    • Energy
    • Crypto
    • ForexHot
    • Tech
  • Sports
  • Lifestyle
  • Videos
Search
Countries
  • Saudi Arabia
  • UAE
  • Kuwait
  • Qatar
  • Bahrain
  • Oman
More Topics
  • Technology
  • Health
  • Entertainment
  • Crypto
  • Forex
  • Stocks
Site Links
  • Business Hub
  • Trending
  • Weather
  • Customize Interests
  • Bookmarks
  • Newsletter
  • Terms
  • Press Release
  • Advertise
  • Contact
© 2023 Gulf Press. All Rights Reserved.
Reading: Immunotherapy drug could help patients avoid surgery
Share
Notification Show More
Recent Saved
Workers in Bucharest face challenges as temperatures rise
World
Dress code guidelines for the Qatari government sector during office hours
Qatar
Court rules in favor of worker after company dismisses him for salary deductions over 6 years, awarding BD 27,000.
Bahrain
UAE to See Almost 30,000 New Millionaires in 5 Years
UAE
Proposed New Labor Law in Bahrain Targets Increasing Job Opportunities
Bahrain
Latest News
Ferrero’s Social Responsibility Project Kinder Joy of moving Beats Traditional PE Curriculum, Tapping into the Cognitive Functions, Motor Coordination and Life Skills of Students
Lifestyle
UAE Ranks Among Top Rugby Markets on TOD as British & Irish Lions Tour Kicks Off
Sports
Darven: A New Leap in AI-Powered Legal Technology Launching from the UAE to the World
Tech
Beat the Heat This Summer with a Chill Out on Dubai Marina
World
Historic Italian City of Assisi to Host International Exhibition “Jordan: Dawn of Christianity”
World
Jordan to Host Iraq in the Final Round of the Asian World Cup Qualifiers After Securing Historic Spot
Sports
The Myriad Redefines Student Living for a Mobile, Urban Generation
UAE
L’Oréal Paris Welcomes Yasmine Sabri as New Brand Ambassador for the Middle East
Lifestyle
Roland Garros 2025: A New Era of Viewing, A Tribute to Legends, and Moments to Remember
Sports World
Bitget Celebrates Bitcoin Pizza Day by Distributing Over 5000 Pizzas in Over 20 Cities Worldwide
Crypto
Bitget Protection Fund Maintains Strength with $561 Million Average Value in April 2025
Business Crypto
Moscow Metro Marks 90 Years with Technological Advancements and Heritage Events
Lifestyle World
Senkron Digital Showcases CyberPact Service at GISEC Global 2025
Gulf UAE
Muhammad Umair Saeed: The Billionaire Tech Architect Powering AI, Drones, Blockchain & Cybersecurity from Dubai to the World
Business Gulf UAE
Barcelona Aims to Recover from European Heartbreak as They Face Real Madrid in La Liga, Chasing Their Third Title of the Season
Sports
Aa
Gulf PressGulf Press
Aa
  • Gulf News
  • World
  • Business
  • Entertainment
  • Lifestyle
  • Sports
  • Videos
Search
  • Home
    • Videos
    • Business Hub
    • Trending
  • Gulf
    • Saudi Arabia
    • UAE
    • Kuwait
    • Qatar
    • Bahrain
    • Oman
  • Business
    • Market Data
    • Crypto
    • Economy
    • Energy
    • Finance
    • Forex
    • Tech
  • More News
    • World
    • Lifestyle
    • Entertainment
    • Sports
Have an existing account? Sign In
Follow US
  • Terms
  • Press Release
  • Advertise
  • Contact
© 2023 Gulf Press. All Rights Reserved.
Gulf Press > Health > Immunotherapy drug could help patients avoid surgery
Health

Immunotherapy drug could help patients avoid surgery

News Room
Last updated: 2024/06/15 at 6:26 AM
News Room
Share
4 Min Read
SHARE

A recent clinical trial has shown promising results in treating mismatch repair deficient (dMMR) tumors with high microsatellite instability (MSI-H) using immunotherapy drug pembrolizumab before surgery instead of chemotherapy for people with stage two or three colorectal cancer. This innovative approach has been found to significantly improve outcomes for patients with this specific type of colorectal cancer, which accounts for about 15% of all cases. The study was presented at the American Society of Clinical Oncology (ASCO) Annual Meeting 2024. Researchers administered three cycles of pembrolizumab before surgery, leading to more than 50% of patients having no signs of cancer after their surgery, a marked improvement compared to standard chemotherapy.

Colorectal cancer, also known as colon cancer or bowel cancer, is a prevalent type of cancer globally, with more than 1.9 million cases diagnosed in 2020 and expected to rise to 3.2 million by 2040. MMR deficient/MSI-H colorectal cancer tumors can be challenging to treat, but the use of pembrolizumab before surgery has shown promising results in improving outcomes for patients with stage two or three colorectal cancer. Pembrolizumab, an immunotherapy drug, works by upregulating the patient’s immune system to recognize and eliminate cancer cells. This approach has been particularly successful in treating deficient dMMR bowel cancers, with the potential to induce long-term remission and even cure, unlike traditional non-targeted treatments like chemotherapy and radiotherapy.

The NEOPRISM-CRC phase II clinical trial focused on pembrolizumab, and the results indicated that giving immunotherapy before surgery can lead to a more significant number of patients being cancer-free post-surgery compared to those receiving chemotherapy. This novel approach aims to shrink the cancer significantly before surgery, potentially eliminating microscopic cancer cells that could lead to future relapse. The study’s primary endpoint is three-year relapse survival rate, with researchers looking to enroll more patients to generate sufficient data and confidence in the effectiveness and long-term benefits of this treatment.

The results of the clinical trial have garnered interest from experts in the field, with Dr. Anton Bilchik highlighting the novel and provocative nature of the study. Immunotherapy has traditionally been used in advanced colon cancer, but this study is the first to explore its efficacy in the early stages of colon cancer before surgery. Dr. Glenn S. Parker emphasized the importance of long-term follow-up to assess the duration of response and cautioned that the promising results of immunotherapy cannot be generalized to all colon cancers. However, with the development of more drugs for both chemotherapy and immunotherapy, future clinical trials will continue to shape individualized treatment strategies based on the molecular genetic profile of patients and their tumors.

Overall, the use of pembrolizumab before surgery in patients with MMR deficient/MSI-H colorectal cancer represents a significant advancement in the treatment of this specific subtype of colorectal cancer. The promising results of the NEOPRISM-CRC trial point towards a potential shift in treatment approaches, focusing on immunotherapy to induce remission and possibly cure patients upfront. As research continues to unravel the nuances of immunotherapy and its efficacy in different cancer types, personalized treatment strategies are likely to play a significant role in shaping the future of cancer care.

Sign Up For Daily Newsletter

Be keep up! Get the latest breaking news delivered straight to your inbox.
I have read and agree to the terms & conditions
By signing up, you agree to our Terms of Use and acknowledge the data practices in our Privacy Policy. You may unsubscribe at any time.
News Room June 15, 2024
Share this Article
Facebook Twitter Copy Link Print
Previous Article ‘Chandu Champion’ Review: Engaging yet inconsistent – News
Next Article ‘Miraculous Escape from the Water Tank’: How One Man Survived the Deadly Fire in Manama Souq’
Leave a comment Leave a comment

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Stay Connected

235.3k Followers Like
69.1k Followers Follow
56.4k Followers Follow
136k Subscribers Subscribe
- Advertisement -
Ad imageAd image

Latest News

Ferrero’s Social Responsibility Project Kinder Joy of moving Beats Traditional PE Curriculum, Tapping into the Cognitive Functions, Motor Coordination and Life Skills of Students
Lifestyle July 14, 2025
UAE Ranks Among Top Rugby Markets on TOD as British & Irish Lions Tour Kicks Off
Sports July 6, 2025
Darven: A New Leap in AI-Powered Legal Technology Launching from the UAE to the World
Tech July 1, 2025
Beat the Heat This Summer with a Chill Out on Dubai Marina
World July 1, 2025

You Might also Like

Health

Mindfulness could be equally effective as antidepressants

October 17, 2024
Health

What is the impact of caffeine on the risk of developing diseases?

October 17, 2024
Health

Scientists discover combination of 14 genes that enhance outcomes

October 16, 2024
Health

Seizure medication demonstrates potential in individuals with no genetic risk

October 16, 2024
Health

Heart disease increases risk, heparin can postpone onset

October 16, 2024
Health

What type of breakfast is most effective for weight loss in women compared to men?

October 15, 2024
Health

How does the brain remove “waste” to protect itself?

October 14, 2024
Health

How does stress, sleep, and gut imbalances affect it?

October 13, 2024
//

Gulf Press is your one-stop website for the latest news and updates about Arabian Gulf and the world, follow us now to get the news that matters to you.

Quick Link

  • Privacy Policy
  • Terms of ue
  • Advertise
  • Contact

How Topics

  • Gulf News
  • International
  • Business
  • Lifestyle

Sign Up for Our Newsletter

Subscribe to our newsletter to get our latest news instantly!

I have read and agree to the terms & conditions
Gulf PressGulf Press
Follow US

© 2023 Gulf Press. All Rights Reserved.

Join Us!

Subscribe to our newsletter and never miss our latest news, podcasts etc..

I have read and agree to the terms & conditions
Zero spam, Unsubscribe at any time.

Removed from reading list

Undo
Welcome Back!

Sign in to your account

Lost your password?